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Structure-based release analysis of the JC virus agnoprotein regions: A role for the hydrophilic surface of the major alpha helix domain in release

Agnoprotein (Agno) is an important regulatory protein of JC virus (JCV), BK virus (BKV) and simian virus 40 (SV40) and these viruses are unable to replicate efficiently in the absence of this protein. Recent 3D–NMR structural data revealed that Agno contains two alpha-helices (a minor and a major) w...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Saribas, A. Sami, White, Martyn K., Safak, Mahmut
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705473/
https://ncbi.nlm.nih.gov/pubmed/28722139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26106
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