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Leveraging blood and tissue CD4+ T cell heterogeneity at the single cell level to identify mechanisms of disease in rheumatoid arthritis

CD4+ T cells have been long known to play an important role in the pathogenesis of rheumatoid arthritis (RA), but the specific cell populations and states that drive the disease have been challenging to identify with low dimensional single cell data and bulk assays. The advent of high dimensional si...

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Detalhes bibliográficos
Publicado no:Curr Opin Immunol
Main Authors: Fonseka, Chamith Y., Rao, Deepak A., Raychaudhuri, Soumya
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705469/
https://ncbi.nlm.nih.gov/pubmed/28888129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2017.08.005
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