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Advances in genetics toward identifying pathogenic cell states of rheumatoid arthritis

Rheumatoid arthritis (RA) risk has a large genetic component (~60%) that is still not fully understood. This has hampered the design of effective treatments that could promise lifelong remission. RA is a polygenic disease with 106 known genome-wide significant associated loci and thousands of small...

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Bibliographic Details
Published in:Immunol Rev
Main Authors: Amariuta, Tiffany, Luo, Yang, Knevel, Rachel, Okada, Yukinori, Raychaudhuri, Soumya
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047592/
https://ncbi.nlm.nih.gov/pubmed/31782165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12827
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