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Engineering the Biocatalytic Selectivity of Iridoid Production in Saccharomyces cerevisiae

Monoterpene indole alkaloids (MIAs) represent a structurally diverse, medicinally essential class of plant derived natural products. The universal MIA building block strictosidine was recently produced in the yeast Saccharomyces cerevisiae, setting the stage for optimization of microbial production....

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Detalhes bibliográficos
Publicado no:Metab Eng
Main Authors: Billingsley, John M., DeNicola, Anthony B., Barber, Joyann S., Tang, Man-Cheng, Horecka, Joe, Chu, Angela, Garg, Neil K., Tang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705256/
https://ncbi.nlm.nih.gov/pubmed/28939278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2017.09.006
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