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HEXIM1 plays a critical role in the inhibition of the androgen receptor by anti-androgens
We show that HEXIM1 (hexamethylene bis-acetamide inducible 1) functions as an AR (androgen receptor) co-repressor as it physically interacts with the AR and is required for the ability of anti-androgens to inhibit androgen-induced target gene expression and cell proliferation. Oncomine™ database and...
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| Udgivet i: | Biochem J |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5705236/ https://ncbi.nlm.nih.gov/pubmed/24844355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140174 |
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