HEXIM1 plays a critical role in the inhibition of the androgen receptor by anti-androgens

We show that HEXIM1 (hexamethylene bis-acetamide inducible 1) functions as an AR (androgen receptor) co-repressor as it physically interacts with the AR and is required for the ability of anti-androgens to inhibit androgen-induced target gene expression and cell proliferation. Oncomine™ database and...

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Vydáno v:Biochem J
Hlavní autoři: Yeh, I-Ju, Song, Kyung, Wittmann, Bryan M., Bai, Xiaodong, Danielpour, David, Montano, Monica M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705236/
https://ncbi.nlm.nih.gov/pubmed/24844355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140174
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