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Chemoenzymatic glycan remodeling of natural and recombinant glycoproteins

N-glycosylation plays important roles in modulating the biological functions of glycoproteins, such as protein folding, stability, and immunogenicity. However, acquiring homogeneous glycoforms of glycoproteins has been a challenging task for functional studies and therapeutic applications. In this c...

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Bibliographic Details
Published in:Methods Enzymol
Main Authors: Yang, Qiang, Wang, Lai-Xi
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705189/
https://ncbi.nlm.nih.gov/pubmed/28935106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.06.006
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