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A Novel Murine Model of Marfan Syndrome Accelerates Aortopathy and Cardiomyopathy
BACKGROUND: Marfan syndrome (MFS) represents a genetic disorder with variable phenotypic expression. The main cardiovascular sequelae of MFS include aortic aneurysm/dissection and cardiomyopathy. While significant advances in the understanding of TGF-β signaling have led to promising therapeutic tar...
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| Publicado no: | Ann Thorac Surg |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5705055/ https://ncbi.nlm.nih.gov/pubmed/28347539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2016.10.077 |
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