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Selective pressure for rapid membrane integration constrains the sequence of bacterial outer membrane proteins

Almost all bacterial outer membrane proteins (OMPs) contain a β barrel domain that serves as a membrane anchor, but the assembly and quality control of these proteins are poorly understood. Here we show that the introduction of a single lipid-facing arginine residue near the middle of the β barrel o...

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Detalles Bibliográficos
Publicado en:Mol Microbiol
Main Authors: Peterson, Janine H., Plummer, Ashlee M., Fleming, Karen G., Bernstein, Harris D.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705044/
https://ncbi.nlm.nih.gov/pubmed/28941249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13845
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