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Expression of tight junction proteins and transporters for xenobiotic metabolism at the blood-CSF barrier during development in the nonhuman primate (P.hamadryas)

The choroid plexus (CP) is rich in barrier mechanisms including transporters and enzymes which can influence drug disposition between blood and brain. We have limited knowledge of their state in fetus. We have studied barrier mechanisms along with metabolism and transporters influencing xenobiotics,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Reprod Toxicol
Hauptverfasser: Ek, C. Joakim, D’Angelo, Barbara, Lehner, Christine, Nathanielsz, Peter, Li, Cun, Mallard, Carina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704986/
https://ncbi.nlm.nih.gov/pubmed/26092209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2015.06.047
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