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MATE transport of the E. coli-derived genotoxin colibactin
Various forms of cancer have been linked to the carcinogenic activities of microorganisms(1–3). The virulent gene island polyketide synthase (pks) produces the secondary metabolite colibactin, a genotoxic molecule(s) causing double-stranded DNA breaks(4) and enhanced colorectal cancer development(5,...
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| Veröffentlicht in: | Nat Microbiol |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5704960/ https://ncbi.nlm.nih.gov/pubmed/27571755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2015.9 |
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