Phylogenomics of Cas4 family nucleases

BACKGROUND: The Cas4 family endonuclease is a component of the adaptation module in many variants of CRISPR-Cas adaptive immunity systems. Unlike most of the other Cas proteins, Cas4 is often encoded outside CRISPR-cas loci (solo-Cas4) and is also found in mobile genetic elements (MGE-Cas4). RESULTS...

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Pubblicato in:BMC Evol Biol
Autori principali: Hudaiberdiev, Sanjarbek, Shmakov, Sergey, Wolf, Yuri I., Terns, Michael P., Makarova, Kira S., Koonin, Eugene V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704561/
https://ncbi.nlm.nih.gov/pubmed/29179671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-017-1081-1
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