Mild endoplasmic reticulum stress ameliorates lipopolysaccharide-induced neuroinflammation and cognitive impairment via regulation of microglial polarization

BACKGROUND: Neuroinflammation, which ultimately leads to neuronal loss, is considered to play a crucial role in numerous neurodegenerative diseases. The neuroinflammatory process is characterized by the activation of glial cells such as microglia. Endoplasmic reticulum (ER) stress is commonly associ...

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Publicado en:J Neuroinflammation
Main Authors: Wang, Yi-wei, Zhou, Qin, Zhang, Xiang, Qian, Qing-qing, Xu, Jia-wen, Ni, Peng-fei, Qian, Yan-ning
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704515/
https://ncbi.nlm.nih.gov/pubmed/29179727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1002-7
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