Lysine trimethylation regulates 78-kDa glucose-regulated protein proteostasis during endoplasmic reticulum stress

The up-regulation of chaperones such as the 78-kDa glucose-regulated protein (GRP78, also referred to as BiP or HSPA5) is part of the adaptive cellular response to endoplasmic reticulum (ER) stress. GRP78 is widely used as a marker of the unfolded protein response, associated with sustained ER stres...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Sieber, Jonas, Wieder, Nicolas, Ostrosky-Frid, Mauricio, Dvela-Levitt, Moran, Aygün, Ozan, Udeshi, Namrata D., Carr, Steven A., Greka, Anna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2017
Pynciau:
Protein Synthesis and Degradation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704472/
https://ncbi.nlm.nih.gov/pubmed/28912266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.797084
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