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Dual Mechanisms for Balancing Th17 and Treg Cell Fate by CREB
Th17 cells, which express the cytokine IL-17A, and master regulator RORγt, are important in the inflammatory response to fungal and bacterial pathogens, but also have a pathogenic role in many inflammatory disorders. In contrast, regulatory T cells (Treg), expressing the Foxp3 transcription factor,...
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| Publié dans: | EBioMedicine |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5704069/ https://ncbi.nlm.nih.gov/pubmed/29129697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.10.031 |
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