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Dual Mechanisms for Balancing Th17 and Treg Cell Fate by CREB

Th17 cells, which express the cytokine IL-17A, and master regulator RORγt, are important in the inflammatory response to fungal and bacterial pathogens, but also have a pathogenic role in many inflammatory disorders. In contrast, regulatory T cells (Treg), expressing the Foxp3 transcription factor,...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Symons, Antony, Ouyang, Wenjun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704069/
https://ncbi.nlm.nih.gov/pubmed/29129697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.10.031
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