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Rare non-coding variants are associated with plasma lipid traits in a founder population

Founder populations are ideally suited for studies on the clinical effects of alleles that are rare in general populations but occur at higher frequencies in these isolated populations. Whole genome sequencing in 98 Hutterites, a founder population of European descent, and subsequent imputation reve...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Igartua, Catherine, Mozaffari, Sahar V., Nicolae, Dan L., Ober, Carole
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704019/
https://ncbi.nlm.nih.gov/pubmed/29180722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16550-8
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