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Systemic clearance and brain distribution of carbazole-based cyanine compounds as Alzheimer’s disease drug candidates
SLM and SLOH, two analogues of carbazole-based cyanine compounds, have been shown to inhibit β-amyloid peptide aggregation in vitro and in Alzheimer’s disease model mice, which could be potentially developed into drugs for disease treatment. To pave the way for further pharmacokinetics-pharmacodynam...
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| Gepubliceerd in: | Sci Rep |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5703966/ https://ncbi.nlm.nih.gov/pubmed/29180684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16635-4 |
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