Synergistic Anti-arrhythmic Effects in Human Atria with Combined Use of Sodium Blockers and Acacetin

Atrial fibrillation (AF) is the most common cardiac arrhythmia. Developing effective and safe anti-AF drugs remains an unmet challenge. Simultaneous block of both atrial-specific ultra-rapid delayed rectifier potassium (K(+)) current (I(Kur)) and the Na(+) current (I(Na)) has been hypothesized to be...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Ni, Haibo, Whittaker, Dominic G., Wang, Wei, Giles, Wayne R., Narayan, Sanjiv M., Zhang, Henggui
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703742/
https://ncbi.nlm.nih.gov/pubmed/29218016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00946
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