Deep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins

Recent functional, proteomic and ribosome profiling studies in eukaryotes have concurrently demonstrated the translation of alternative open-reading frames (altORFs) in addition to annotated protein coding sequences (CDSs). We show that a large number of small proteins could in fact be coded by thes...

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Samandi, Sondos, Roy, Annie V, Delcourt, Vivian, Lucier, Jean-François, Gagnon, Jules, Beaudoin, Maxime C, Vanderperre, Benoît, Breton, Marc-André, Motard, Julie, Jacques, Jean-François, Brunelle, Mylène, Gagnon-Arsenault, Isabelle, Fournier, Isabelle, Ouangraoua, Aida, Hunting, Darel J, Cohen, Alan A, Landry, Christian R, Scott, Michelle S, Roucou, Xavier
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2017
Sujets:
Biochemistry and Chemical Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703645/
https://ncbi.nlm.nih.gov/pubmed/29083303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27860
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