Para-hydroxyphenylpyruvate inhibits the pro-inflammatory stimulation of macrophage preventing LPS-mediated nitro-oxidative unbalance and immunometabolic shift

Targeting metabolism is emerging as a promising therapeutic strategy for modulation of the immune response in human diseases. In the presented study we used the lipopolysaccharide (LPS)-mediated activation of RAW 264.7 macrophage-like cell line as a model to investigate changes in the metabolic phen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Scrima, Rosella, Menga, Marta, Pacelli, Consiglia, Agriesti, Francesca, Cela, Olga, Piccoli, Claudia, Cotoia, Antonella, De Gregorio, Alessandra, Gefter, Julia V., Cinnella, Gilda, Capitanio, Nazzareno
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703549/
https://ncbi.nlm.nih.gov/pubmed/29176872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188683
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