Charged residues in the H-NS linker drive DNA binding and gene silencing in single cells

Nucleoid-associated proteins (NAPs) facilitate chromosome organization in bacteria, but the precise mechanism remains elusive. H-NS is a NAP that also plays a major role in silencing pathogen genes. We used genetics, single-particle tracking in live cells, superresolution microscopy, atomic force mi...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Gao, Yunfeng, Foo, Yong Hwee, Winardhi, Ricksen S., Tang, Qingnan, Yan, Jie, Kenney, Linda J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703333/
https://ncbi.nlm.nih.gov/pubmed/29109287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716721114
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