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Proof of region-specific multipotent progenitors in human breast epithelia

The human breast parenchyma consists of collecting ducts and terminal duct lobular units (TDLUs). The TDLU is the site of origin of most breast cancers. The reason for such focal susceptibility to cancer remains poorly understood. Here, we take advantage of a region-specific heterogeneity in luminal...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fridriksdottir, Agla J., Villadsen, René, Morsing, Mikkel, Klitgaard, Marie Christine, Kim, Jiyoung, Petersen, Ole William, Rønnov-Jessen, Lone
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703323/
https://ncbi.nlm.nih.gov/pubmed/29109259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714063114
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