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Sea anemone model has a single Toll-like receptor that can function in pathogen detection, NF-κB signal transduction, and development

In organisms from insects to vertebrates, Toll-like receptors (TLRs) are primary pathogen detectors that activate downstream pathways, specifically those that direct expression of innate immune effector genes. TLRs also have roles in development in many species. The sea anemone Nematostella vectensi...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Brennan, Joseph J., Messerschmidt, Jonathan L., Williams, Leah M., Matthews, Bryan J., Reynoso, Marinaliz, Gilmore, Thomas D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703304/
https://ncbi.nlm.nih.gov/pubmed/29109290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711530114
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