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Sea anemone model has a single Toll-like receptor that can function in pathogen detection, NF-κB signal transduction, and development

In organisms from insects to vertebrates, Toll-like receptors (TLRs) are primary pathogen detectors that activate downstream pathways, specifically those that direct expression of innate immune effector genes. TLRs also have roles in development in many species. The sea anemone Nematostella vectensi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Brennan, Joseph J., Messerschmidt, Jonathan L., Williams, Leah M., Matthews, Bryan J., Reynoso, Marinaliz, Gilmore, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703304/
https://ncbi.nlm.nih.gov/pubmed/29109290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711530114
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