An RNA structure-mediated, posttranscriptional model of human α-1-antitrypsin expression

Chronic obstructive pulmonary disease (COPD) affects over 65 million individuals worldwide, where α-1-antitrypsin deficiency is a major genetic cause of the disease. The α-1-antitrypsin gene, SERPINA1, expresses an exceptional number of mRNA isoforms generated entirely by alternative splicing in the...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Corley, Meredith, Solem, Amanda, Phillips, Gabriela, Lackey, Lela, Ziehr, Benjamin, Vincent, Heather A., Mustoe, Anthony M., Ramos, Silvia B. V., Weeks, Kevin M., Moorman, Nathaniel J., Laederach, Alain
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703279/
https://ncbi.nlm.nih.gov/pubmed/29109288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706539114
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker