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Protein engineering of the chemokine CCL20 prevents psoriasiform dermatitis in an IL-23–dependent murine model
Psoriasis is a chronic inflammatory skin disease characterized by the infiltration of T cell and other immune cells to the skin in response to injury or autoantigens. Conventional, as well as unconventional, γδ T cells are recruited to the dermis and epidermis by CCL20 and other chemokines. Together...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5703275/ https://ncbi.nlm.nih.gov/pubmed/29109267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704958114 |
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