Reconstitution of the core of the malaria parasite glideosome with recombinant Plasmodium class XIV myosin A and Plasmodium actin

Motility of the apicomplexan malaria parasite Plasmodium falciparum is enabled by a multiprotein glideosome complex, whose core is the class XIV myosin motor, PfMyoA, and a divergent Plasmodium actin (PfAct1). Parasite motility is necessary for host-cell invasion and virulence, but studying its mole...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bookwalter, Carol S., Tay, Chwen L., McCrorie, Rama, Previs, Michael J., Lu, Hailong, Krementsova, Elena B., Fagnant, Patricia M., Baum, Jake, Trybus, Kathleen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702669/
https://ncbi.nlm.nih.gov/pubmed/28978649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.813972
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