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Integrated approaches to understanding antipsychotic drug action at GPCRs

The G-protein coupled receptor (GPCR) family of genes represents one of the largest druggable families of genes in the human genome. This is evident by the fact that approximately 30% of currently marketed drugs target GPCRs. However, many of these drugs are limited in their clinical potential as th...

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Publicat a:Curr Opin Cell Biol
Autors principals: Urs, Nikhil M., Nicholls, Peter J., Caron, Marc G.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702556/
https://ncbi.nlm.nih.gov/pubmed/24680431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2013.11.002
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