Wnt/β-catenin Signaling Pathway Regulates Specific lncRNAs That Impact Dermal Fibroblasts and Skin Fibrosis

Wnt/β-catenin signaling is required for embryonic dermal fibroblast cell fate, and dysregulation of this pathway is sufficient to promote fibrosis in adult tissue. The downstream modulators of Wnt/β-catenin signaling required for controlling cell fate and dermal fibrosis remain poorly understood. Th...

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Bibliographic Details
Published in:Front Genet
Main Authors: Mullin, Nathaniel K., Mallipeddi, Nikhil V., Hamburg-Shields, Emily, Ibarra, Beatriz, Khalil, Ahmad M., Atit, Radhika P.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702388/
https://ncbi.nlm.nih.gov/pubmed/29209359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2017.00183
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