Absence of the Non-Signalling Chemerin Receptor CCRL2 Exacerbates Acute Inflammatory Responses In Vivo

Chemerin is a chemotactic protein that induces migration of several immune cells including macrophages, immature dendritic cells, and NK cells. Chemerin binds to three G protein-coupled receptors (GPCRs), including CCRL2. The exact function of CCRL2 remains unclear. CCRL2 expression is rapidly upreg...

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Vydáno v:Front Immunol
Hlavní autoři: Regan-Komito, Daniel, Valaris, Sophia, Kapellos, Theodore S., Recio, Carlota, Taylor, Lewis, Greaves, David R., Iqbal, Asif J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702352/
https://ncbi.nlm.nih.gov/pubmed/29209334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01621
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