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miR-145-5p/Nurr1/TNF-α Signaling-Induced Microglia Activation Regulates Neuron Injury of Acute Cerebral Ischemic/Reperfusion in Rats

Nurr1 is a member of the nuclear receptor 4 family of orphan nuclear receptors that is decreased in inflammatory responses and leads to neurons death in Parkinson’s disease. Abnormal expression of Nurr1 have been attributed to various signaling pathways, but little is known about microRNAs (miRNAs)...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Xie, Xuemei, Peng, Li, Zhu, Jin, Zhou, Yang, Li, Lingyu, Chen, Yanlin, Yu, Shanshan, Zhao, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702297/
https://ncbi.nlm.nih.gov/pubmed/29209166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00383
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