LncRNA MALAT1 silencing protects against cerebral ischemia-reperfusion injury through miR-145 to regulate AQP4

BACKGROUND: The present study aimed to verify whether long noncoding RNA (lncRNA) MALAT1 is involved in brain tissue damage induced by ischemia-reperfusion injury, and to explore the mechanism by which MALAT1 regulates aquaporin 4 (AQP4). METHODS: In this study, we established glucose deprivation (O...

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Pubblicato in:J Biomed Sci
Autori principali: Wang, Hongwei, Zheng, Xiaoxiao, Jin, Jing, Zheng, Li, Guan, Ting, Huo, Yangfan, Xie, Shufen, Wu, Ying, Chen, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059719/
https://ncbi.nlm.nih.gov/pubmed/32138732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-020-00635-0
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