Autocrine parathyroid hormone-like hormone promotes intrahepatic cholangiocarcinoma cell proliferation via increased ERK/JNK-ATF2-cyclinD1 signaling

BACKGROUND AND AIMS: Intrahepatic cholangiocarcinoma (ICC) is an aggressive tumor with a high fatality rate. It was recently found that parathyroid hormone-like hormone (PTHLH) was frequently overexpressed in ICC compared with non-tumor tissue. This study aimed to elucidate the underlying mechanisms...

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Detalles Bibliográficos
Publicado en:J Transl Med
Main Authors: Tang, Jing, Liao, Yan, He, Shuying, Shi, Jie, Peng, Liang, Xu, Xiaoping, Xie, Fang, Diao, Na, Huang, Jinlan, Xie, Qian, Lin, Chuang, Luo, Xiaoying, Liao, Kaili, Ma, Juanjuan, Li, Jingyi, Zhou, Daichao, Li, Zhijun, Xu, Jun, Zhong, Chao, Wang, Guozhen, Bai, Lan
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702246/
https://ncbi.nlm.nih.gov/pubmed/29178939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1342-1
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