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A multiscale modeling study of particle size effects on the tissue penetration efficacy of drug-delivery nanoparticles

BACKGROUND: Particle size is a key parameter for drug-delivery nanoparticle design. It is believed that the size of a nanoparticle may have important effects on its ability to overcome the transport barriers in biological tissues. Nonetheless, such effects remain poorly understood. Using a multiscal...

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Publicat a:BMC Syst Biol
Autors principals: Islam, Mohammad Aminul, Barua, Sutapa, Barua, Dipak
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702122/
https://ncbi.nlm.nih.gov/pubmed/29178887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0491-4
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