Anteroposterior polarity and elongation in the absence of extra-embryonic tissues and of spatially localised signalling in gastruloids: mammalian embryonic organoids

The establishment of the anteroposterior (AP) axis is a crucial step during animal embryo development. In mammals, genetic studies have shown that this process relies on signals spatiotemporally deployed in the extra-embryonic tissues that locate the position of the head and the onset of gastrulatio...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Turner, David A., Girgin, Mehmet, Alonso-Crisostomo, Luz, Trivedi, Vikas, Baillie-Johnson, Peter, Glodowski, Cherise R., Hayward, Penelope C., Collignon, Jérôme, Gustavsen, Carsten, Serup, Palle, Steventon, Benjamin, P. Lutolf, Matthias, Arias, Alfonso Martinez
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Stem Cells and Regeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702072/
https://ncbi.nlm.nih.gov/pubmed/28951435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.150391
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