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Sustained sensitizing effects of tumor necrosis factor alpha on sensory nerves in lung and airways

Tumor necrosis factor alpha (TNFα) plays a significant role in the pathogenesis of airway inflammatory diseases. Inhalation of aerosolized TNFα induced airway hyperresponsiveness accompanied by airway inflammation in healthy human subjects, but the underlying mechanism is not fully understood. We re...

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Bibliographic Details
Published in:Pulm Pharmacol Ther
Main Authors: Lin, Ruei-Lung, Gu, Qihai, Khosravi, Mehdi, Lee, Lu-Yuan
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701849/
https://ncbi.nlm.nih.gov/pubmed/28587842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pupt.2017.06.001
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