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Hypersensitivity of Vagal Pulmonary Afferents Induced by Tumor Necrosis Factor Alpha in Mice

Tumor necrosis factor alpha (TNFα), a pro-inflammatory cytokine, plays a significant role in the pathogenesis of allergic asthma. Inhalation of TNFα also induces airway hyperresponsiveness in healthy human subjects, and the underlying mechanism is not fully understood. A recent study reported that T...

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Pubblicato in:Front Physiol
Autori principali: Lin, Ruei-Lung, Gu, Qihai, Lee, Lu-Yuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470033/
https://ncbi.nlm.nih.gov/pubmed/28659824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00411
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