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Pulmonary chemoreflex responses are potentiated by tumor necrosis factor-alpha in mice

Inhalation of tumor necrosis factor-alpha (TNF-α), a proinflammatory cytokine, induces airway hyperresponsiveness, and the underlying mechanism is not fully understood. Hypersensitivity of vagal bronchopulmonary C-fiber afferents is known to contribute to the airway hyperresponsiveness during an air...

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Hlavní autoři: Lin, Ruei-Lung, Lin, Yu-Jung, Geer, Marcus J., Kryscio, Richard, Lee, Lu-Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680829/
https://ncbi.nlm.nih.gov/pubmed/23539315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01301.2012
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