MGMT promoter methylation as a potential prognostic marker for acute leukemia

INTRODUCTION: It has been proved that genetic and epigenetic changes play a significant role in the development and progression of acute leukemia. The aim of our study was to evaluate the frequency and prognostic implications of genetic and epigenetic alterations in p15, MGMT, DNMT3A and TP53 genes...

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Bibliographic Details
Published in:Arch Med Sci
Main Authors: Sobieszkoda, Dominika, Czech, Joanna, Gablo, Natalia, Kopanska, Marta, Tabarkiewicz, Jacek, Kolacinska, Agnieszka, Robak, Tadeusz, Zawlik, Izabela
Format: Artigo
Language:Inglês
Published: Termedia Publishing House 2017
Subjects:
Clinical Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701700/
https://ncbi.nlm.nih.gov/pubmed/29181075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2017.71067
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