CXL-1020, a Novel Nitroxyl (HNO) Prodrug, Is More Effective than Milrinone in Models of Diastolic Dysfunction—A Cardiovascular Therapeutic: An Efficacy and Safety Study in the Rat

The nitroxyl (HNO) prodrug, CXL-1020, induces vasorelaxation and improves cardiac function in canine models and patients with systolic heart failure (HF). HNO's unique mechanism of action may be applicable to a broader subset of cardiac patients. This study investigated the load-independent saf...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Roof, Steve R., Ueyama, Yukie, Mazhari, Reza, Hamlin, Robert L., Hartman, J. Craig, Ziolo, Mark T., Reardon, John E., del Rio, Carlos L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701606/
https://ncbi.nlm.nih.gov/pubmed/29209225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00894
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados