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IFN-λ suppresses intestinal inflammation by non-translational regulation of neutrophil function

Interferon-λ (IFN-λ) is a central regulator of mucosal immunity; however, its signaling specificity relative to that of type I interferons is poorly defined. IFN-λ can induce antiviral interferon-stimulated genes (ISGs) in epithelia, while the effect of IFN-λ in non-epithelial cells remains unclear....

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Publicat a:Nat Immunol
Autors principals: Broggi, Achille, Tan, Yunhao, Granucci, Francesca, Zanoni, Ivan
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701513/
https://ncbi.nlm.nih.gov/pubmed/28846084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3821
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