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Lack of Adipocyte-Fndc5/Irisin Expression and Secretion Reduces Thermogenesis and Enhances Adipogenesis

Irisin is a browning-stimulating molecule secreted from the fibronectin type III domain containing 5 precursor (FNDC5) by muscle tissue upon exercise stimulation. Despite its beneficial role, there is an unmet and clamorous need to discern many essential aspects of this protein and its mechanism of...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Pérez-Sotelo, D., Roca-Rivada, A., Baamonde, I., Baltar, J., Castro, A. I., Domínguez, E., Collado, M., Casanueva, F. F., Pardo, M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701255/
https://ncbi.nlm.nih.gov/pubmed/29176631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16602-z
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