Quenching protein dynamics interferes with HIV capsid maturation

Maturation of HIV-1 particles encompasses a complex morphological transformation of Gag via an orchestrated series of proteolytic cleavage events. A longstanding question concerns the structure of the C-terminal region of CA and the peptide SP1 (CA–SP1), which represents an intermediate during matur...

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Publicado no:Nat Commun
Main Authors: Wang, Mingzhang, Quinn, Caitlin M., Perilla, Juan R., Zhang, Huilan, Shirra Jr., Randall, Hou, Guangjin, Byeon, In-Ja, Suiter, Christopher L., Ablan, Sherimay, Urano, Emiko, Nitz, Theodore J., Aiken, Christopher, Freed, Eric O., Zhang, Peijun, Schulten, Klaus, Gronenborn, Angela M., Polenova, Tatyana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701193/
https://ncbi.nlm.nih.gov/pubmed/29176596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01856-y
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