Mesenchymal stem cells derived exosomes and microparticles protect cartilage and bone from degradation in osteoarthritis

Mesenchymal stem or stromal cells (MSCs) exert chondroprotective effects in preclinical models of osteoarthritis (OA). Most of their therapeutic effects are mediated via soluble mediators, which can be conveyed within extracellular vesicles (EVs). The objective of the study was to compare the respec...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Cosenza, Stella, Ruiz, Maxime, Toupet, Karine, Jorgensen, Christian, Noël, Danièle
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701135/
https://ncbi.nlm.nih.gov/pubmed/29176667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15376-8
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