Monocyte-derived exosomes upon exposure to cigarette smoke condensate alter their characteristics and show protective effect against cytotoxicity and HIV-1 replication

Smoking is known to exacerbate HIV-1 pathogenesis, especially in monocytes, through the oxidative stress pathway. Exosomes are known to alter HIV-1 pathogenesis through inter-cellular communication. However, the role of exosomes in smoking-mediated HIV-1 pathogenesis is unknown. In this study, we in...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Haque, Sanjana, Sinha, Namita, Ranjit, Sabina, Midde, Narasimha M., Kashanchi, Fatah, Kumar, Santosh
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701054/
https://ncbi.nlm.nih.gov/pubmed/29170447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16301-9
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