MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance

Intratumoral phenotypic heterogeneity has been described in many tumor types, where it can contribute to drug resistance and disease recurrence. We analyzed ductal and neuroendocrine markers in pancreatic ductal adenocarcinoma, revealing heterogeneous expression of the neuroendocrine marker Synaptop...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Farrell, Amy S., Joly, Meghan Morrison, Allen-Petersen, Brittany L., Worth, Patrick J., Lanciault, Christian, Sauer, David, Link, Jason, Pelz, Carl, Heiser, Laura M., Morton, Jennifer P., Muthalagu, Nathiya, Hoffman, Megan T., Manning, Sara L., Pratt, Erica D., Kendsersky, Nicholas D., Egbukichi, Nkolika, Amery, Taylor S., Thoma, Mary C., Jenny, Zina P., Rhim, Andrew D., Murphy, Daniel J., Sansom, Owen J., Crawford, Howard C., Sheppard, Brett C., Sears, Rosalie C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701042/
https://ncbi.nlm.nih.gov/pubmed/29170413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01967-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados