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Metabolic Differences in Glutamine Utilization Lead to Metabolic Vulnerabilities in Prostate Cancer

The new oncologic paradigm of precision medicine is focused on identifying metabolic, proteomic, transcriptomic and genomic variabilities in tumors that can be exploited to tailor treatments and improve patient outcomes. Metabolic changes are a hallmark of cancer, and inhibition of metabolic pathway...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zacharias, Niki Marie, McCullough, Christopher, Shanmugavelandy, Sriram, Lee, Jaehyuk, Lee, Youngbok, Dutta, Prasanta, McHenry, James, Nguyen, Linda, Norton, William, Jones, Lawrence W., Bhattacharya, Pratip K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701017/
https://ncbi.nlm.nih.gov/pubmed/29170516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16327-z
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