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DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells
Accumulating evidence suggests that exogenous cellular stress induces PD-L1 upregulation in cancer. A DNA double-strand break (DSB) is the most critical type of genotoxic stress, but the involvement of DSB repair in PD-L1 expression has not been investigated. Here we show that PD-L1 expression in ca...
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| Udgivet i: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5701012/ https://ncbi.nlm.nih.gov/pubmed/29170499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01883-9 |
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