DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells

Accumulating evidence suggests that exogenous cellular stress induces PD-L1 upregulation in cancer. A DNA double-strand break (DSB) is the most critical type of genotoxic stress, but the involvement of DSB repair in PD-L1 expression has not been investigated. Here we show that PD-L1 expression in ca...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Sato, Hiro, Niimi, Atsuko, Yasuhara, Takaaki, Permata, Tiara Bunga Mayang, Hagiwara, Yoshihiko, Isono, Mayu, Nuryadi, Endang, Sekine, Ryota, Oike, Takahiro, Kakoti, Sangeeta, Yoshimoto, Yuya, Held, Kathryn D., Suzuki, Yoshiyuki, Kono, Koji, Miyagawa, Kiyoshi, Nakano, Takashi, Shibata, Atsushi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701012/
https://ncbi.nlm.nih.gov/pubmed/29170499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01883-9
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