Whole blood stabilization for the microfluidic isolation and molecular characterization of circulating tumor cells

Precise rare-cell technologies require the blood to be processed immediately or be stabilized with fixatives. Such restrictions limit the translation of circulating tumor cell (CTC)-based liquid biopsy assays that provide accurate molecular data in guiding clinical decisions. Here we describe a meth...

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Udgivet i:Nat Commun
Main Authors: Wong, Keith H. K., Tessier, Shannon N., Miyamoto, David T., Miller, Kathleen L., Bookstaver, Lauren D., Carey, Thomas R., Stannard, Cleo J., Thapar, Vishal, Tai, Eric C., Vo, Kevin D., Emmons, Erin S., Pleskow, Haley M., Sandlin, Rebecca D., Sequist, Lecia V., Ting, David T., Haber, Daniel A., Maheswaran, Shyamala, Stott, Shannon L., Toner, Mehmet
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700979/
https://ncbi.nlm.nih.gov/pubmed/29170510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01705-y
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